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{"id":7993,"date":"2015-12-28T10:15:50","date_gmt":"2015-12-28T08:15:50","guid":{"rendered":"https:\/\/www.coolkadin.com\/?p=7993"},"modified":"2015-12-28T10:15:50","modified_gmt":"2015-12-28T08:15:50","slug":"bebegin-akciger-gelisimi-icin-steroid-ilac-uygulanmasi","status":"publish","type":"post","link":"https:\/\/www.coolkadin.com\/bebegin-akciger-gelisimi-icin-steroid-ilac-uygulanmasi.html","title":{"rendered":"BEBE\u011e\u0130N AKC\u0130\u011eER GEL\u0130\u015e\u0130M\u0130 \u0130\u00c7\u0130N STERO\u0130D \u0130LA\u00c7 UYGULANMASI"},"content":{"rendered":"

Erken do\u011fum risklerinde ya da erken do\u011fumda antenatal kortikostreroid ila\u00e7lar uygulanabilir. Erken do\u011fum, do\u011fumun 37. Gebelik haftas\u0131 dolmadan ya da 36. Gebelik haftas\u0131ndan \u00f6nce ya\u015fanmas\u0131 durumudur. Erken do\u011fum riski olduk\u00e7a ciddi bir sorundur. 36. Gebelik haftas\u0131nda bebek hen\u00fcz geli\u015fimini tamamlayamam\u0131\u015ft\u0131r. S\u00f6z konusu olan gebelik haftalar\u0131nda bebek \u00e7e\u015fitli organ ve i\u015flevleri bak\u0131m\u0131ndan geli\u015fmemi\u015ftir. Bu sebeple erken do\u011fumun ya\u015fanmamas\u0131, \u00f6nlenmesi i\u00e7in \u00e7e\u015fitli tedbirler al\u0131n\u0131r. Bu durum ger\u00e7ekle\u015fmez ise, bebek d\u00fcnyaya geldi\u011finde \u00e7e\u015fitli sorunlar da g\u00f6zlemlenir. Bu sorunlardan baz\u0131lar\u0131:<\/p>\n

Solunum problemleri,
\nGeli\u015fim gerili\u011fi,
\nYo\u011fun bak\u0131m ihtiyac\u0131,
\nEnfeksiyon say\u0131labilir.
\nErken do\u011fum riski durumunda,solunum s\u0131k\u0131nt\u0131lar\u0131n\u0131 \u00f6nlemek ad\u0131na \u00e7e\u015fitli \u00f6nlemler al\u0131n\u0131r. Solunum sorunlar\u0131n\u0131 \u00f6nlemek ad\u0131na uygulanan antenatal kortikosteroid , toplum aras\u0131nda bebe\u011fin akci\u011ferlerinin geli\u015fmesi i\u00e7in yap\u0131lan i\u011fne olarak bilinir.<\/p>\n

Anne karn\u0131nda bebe\u011fin akci\u011fer geli\u015fimi:<\/strong><\/p>\n

Anne aday\u0131n\u0131n karn\u0131nda bebe\u011fin akci\u011fer geli\u015fimi, 26. Gebelik haftas\u0131ndan itibaren ba\u015flar. 26. Gebelik haftas\u0131nda akci\u011ferlerde alveoller\u0131n geli\u015fimi meydana gelir. Bunun d\u0131\u015f\u0131nda s\u00fcrfaktan \u00fcretimi de bu haftadan itibaren ba\u015flar. S\u00fcrfaktan \u015feklinde tabir edilen madde, akci\u011ferlerin fonksiyonlar\u0131n\u0131n yerine getirilmesinde ve solunum yap\u0131labilmesinde rol oynayan en \u00f6nemli madde olmaktad\u0131r. Bundan dolay\u0131 da solunum problemleri ya\u015fayan yenido\u011fan bebeklere ila\u00e7 \u015feklinde uygulanabilmektedir. Bebe\u011fin akci\u011fer geli\u015fimi 34. Gebelik haftas\u0131na gelindi\u011finde olduk\u00e7a geli\u015fme kaydetmi\u015ftir. Bundan dolay\u0131 da bu akci\u011fer geli\u015ftirici ila\u00e7 tedavileri bu haftaya dek kullan\u0131l\u0131r. Elbette ki 34. Gebelik haftas\u0131nda b\u00fct\u00fcn bebeklerin akci\u011fer geli\u015fimi ilerleme kaydetmez. Her bebe\u011fin geli\u015fim h\u0131z\u0131 ve \u00f6zelli\u011fi birbirinden farkl\u0131d\u0131r. 34. Gebelik haftas\u0131ndan sonra bebeklerin hi\u00e7birinde solunum problemleri ya\u015fanmayaca\u011f\u0131n\u0131 s\u00f6ylemek m\u00fcmk\u00fcn de\u011fildir. Ancak 34. haftadan sonra d\u00fcnyaya gelen bebeklerde de solunum ve di\u011fer sistem sorunlar nispeten daha az meydana gelir. 34. Gebelik haftas\u0131ndan sonra da antenatal steroidler akci\u011fer geli\u015fimi v.b sebeplerle uygulanabilir mi, konusunda \u00e7e\u015fitli ara\u015ft\u0131rmalar yap\u0131lm\u0131\u015ft\u0131r.Ancak bu konuda g\u00f6r\u00fc\u015f birli\u011fine var\u0131lamam\u0131\u015ft\u0131r.<\/p>\n

Kortikosteroid \u0130la\u00e7lar:<\/strong><\/p>\n

Bu ila\u00e7lar temelde iki ayr\u0131lmaktad\u0131r. Bunlar: betametazon ve deksametazondur.G\u00fcn\u00fcm\u00fczde en fazla uygulanan \u00e7e\u015fidi betamatazondur. Bu ila\u00e7lar anne aday\u0131n\u0131n karn\u0131nda bulunan bebe\u011fin akci\u011fer geli\u015fimini h\u0131zland\u0131rmay\u0131 ama\u00e7lar. Bu sayede olas\u0131 bir erken do\u011fum ard\u0131ndan solunum problemleri ile kar\u015f\u0131la\u015fmamas\u0131 sa\u011flan\u0131r. Bu sayede de: nekrotizas enterokolit, periventrik\u00fcler l\u00f6komalazi, intraventrik\u00fcler kanama gibi farkl\u0131 sorunlar\u0131n meydana gelme riskini minimuma d\u00fc\u015f\u00fcrmeyi ama\u00e7lar. Betametazonun daha yayg\u0131n olarak kullan\u0131lmas\u0131n\u0131n bir sebebi de, deksametazon\u2019un bebe\u011fin n\u00f6rolojik ve davran\u0131\u015fsal \u00e7e\u015fitli i\u015flevleri \u00fczerine olumlu olmayan etkilerinin \u00e7e\u015fitli \u00e7al\u0131\u015fmalarda bildirilmesidir.<\/p>\n

Kortikosteroid ila\u00e7lar nas\u0131l kullan\u0131l\u0131r?<\/strong><\/p>\n

Betametazon\u2019un g\u00fcn\u00fcm\u00fczde en fazla kullan\u0131lan bi\u00e7imi, 24-34 gebelik haftalar\u0131 aras\u0131nda erken do\u011fum riski s\u00f6z konusu olan anne adaylar\u0131nda 24 saat ara ile iki defa 12 mg olmak \u00fczere, toplamda 24 mg intramuskuler y\u00f6ntemle kullan\u0131l\u0131r. Bu y\u00f6ntemde kal\u00e7aya kas i\u00e7ine i\u011fne yap\u0131l\u0131r. \u00c7o\u011ful gebelikler i\u00e7in de ayn\u0131 doz s\u00f6z konusudur.<\/p>\n

Bu ila\u00e7lar do\u011frudan bebe\u011fe uygulanmaz. Anne aday\u0131na uygulan\u0131r. Anne aday\u0131na verilen ila\u00e7 da plasenta ile bebe\u011fe aktar\u0131l\u0131r ve etki eder.<\/p>\n

Kortikosteroid ila\u00e7 tedavisinin avantajlar\u0131:<\/strong><\/p>\n

Do\u011fumun ger\u00e7ekle\u015fmesi ard\u0131ndan bebekte solunum problemlerinin g\u00f6r\u00fclme oran\u0131 olduk\u00e7ad\u00fc\u015fer.
\nYenido\u011fan\u0131n oksijen gereksinimi ve solunum deste\u011fi yap\u0131lma zorunlulu\u011fu azal\u0131r.
\nKortokosteroid ila\u00e7lar, akci\u011fer i\u015flevi bak\u0131m\u0131ndan olduk\u00e7a m\u00fchim bir madde olan s\u00fcrfaktan\u2019\u0131 artt\u0131r\u0131r. Bu sayede akci\u011fer kapasitesini artt\u0131r\u0131r ve kompliyans\u0131n\u0131 artt\u0131r\u0131r.
\nBeyin i\u00e7erisinde bulunan ventrik\u00fcler bo\u015fluklara kanama olma riskini d\u00fc\u015f\u00fcr\u00fcr.
\nBarsaklarda kanlanman\u0131n bozulma sorunu i\u00e7in riski d\u00fc\u015f\u00fcr\u00fcr.
\nYenido\u011fan \u00f6l\u00fcmlerin azalmas\u0131n\u0131 sa\u011flar.<\/p>\n","protected":false},"excerpt":{"rendered":"

Erken…<\/p>\n","protected":false},"author":4,"featured_media":7994,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1523],"tags":[5646,5642,5648,5644,5647,5643,5645,5649],"_links":{"self":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/7993"}],"collection":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/comments?post=7993"}],"version-history":[{"count":0,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/7993\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media\/7994"}],"wp:attachment":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media?parent=7993"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/categories?post=7993"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/tags?post=7993"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}