\u0130kili tarama testi gebelikte bebekte olabilecek baz\u0131 kromozomal anomalileri ara\u015ft\u0131rmak i\u00e7in yap\u0131lan bir testtir.<\/p>\n

GEBEL\u0130KTE (HAM\u0130LEL\u0130KTE) \u0130K\u0130L\u0130 TEST NED\u0130R?<\/strong>
\n 1 ) \u0130kili test nedir? \u0130kili tarama testin yap\u0131lmas\u0131nda ki ama\u00e7 nedir?<\/strong>
\n2000 y\u0131l\u0131ndan beri, d\u00fcnya \u00e7ap\u0131nda ve \u00fclkemizde kullan\u0131ma giren ilk trimester tarama testinin amac\u0131, down sendromunun erken hamilelik haftalar\u0131 i\u00e7erisinde tespit edilmesidir.\u2028\u2028\u0130kli tarama testi, ikli test, ilk trimester tarama testi, 11 ile 14 haftalar aras\u0131 tarama testi veya double test olarak ta ifade edilmektedir.<\/p>\n

\u20282 ) Kimlerde anomalili (do\u011fu\u015ftan sakat) bebek do\u011furma riski g\u00f6r\u00fcl\u00fcr?\u2028<\/strong><\/p>\n

35 ya\u015f\u0131ndan sonra hamile olan kad\u0131nlarda, genetik olarak sa\u011fl\u0131k sorunu bulunanlarda, akraba evlili\u011fi yapanlarda, ailelerinde do\u011fu\u015ftan sakatl\u0131k bulunanlarda, daha \u00f6nce anomalili (sakat) bebek do\u011furmu\u015f olan annelerde, \u00fcremeye yard\u0131mc\u0131 y\u00f6ntemler sayesinde hamile olanlarda (t\u00fcp bebek ve mikroenjeksiyon y\u00f6ntemleri gibi), d\u00fc\u015f\u00fck (abortus) veya rahim i\u00e7inde bebek \u00f6l\u00fcm\u00fc ya\u015fam\u0131\u015f olan ki\u015filerde, anomalili bebek do\u011furma riskleri g\u00f6r\u00fclmektedir.<\/p>\n

3 ) \u0130kili testte nelere bak\u0131l\u0131r?<\/strong><\/p>\n

Anne aday\u0131n\u0131n son adet tarihine bak\u0131larak, 11 ile 14. hamilelik haftalar\u0131 aras\u0131nda yap\u0131lan testte, anne aday\u0131ndan al\u0131nan kan \u00f6rne\u011finde serbest \u03b2-HCG ve PAPP-A biyokimyasal seviyeler incelenir.<\/p>\n

HCG hormonu, sadece hamilelik d\u00f6nemi i\u00e7erisinde salg\u0131lanan bir hormondur. Hatta hamilelik testlerinin de\u011ferlendirilmesi yap\u0131ld\u0131\u011f\u0131 zaman dahi, HCG hormonu \u00f6l\u00e7\u00fclmektedir.<\/p>\n

Ayn\u0131 zamanda ultrason arac\u0131l\u0131\u011f\u0131 ile bebe\u011fin ense derisi i\u00e7erisinde yer alan s\u0131v\u0131n\u0131n \u00f6l\u00e7\u00fcm\u00fc de yap\u0131lmaktad\u0131r. Bu \u00f6l\u00e7\u00fcme \u201cense kal\u0131nl\u0131\u011f\u0131\u201d (NT) denir. Ense kal\u0131nl\u0131\u011f\u0131, ense pilisi veya \u201cnuchal translucency\u201d olarak ifade edildi\u011finden dolay\u0131, t\u0131bbi literat\u00fcrde genellikle \u201cNT\u201d k\u0131saltmas\u0131 ile ifade edilmektedir. \u2028\u2028\u0130kili test taramas\u0131 s\u0131ras\u0131nda, kanda bulunan biokimyasal de\u011ferler ile beraber, ense kal\u0131nl\u0131\u011f\u0131 \u00f6l\u00e7\u00fcmleri de beraberce de\u011ferlendirme alt\u0131na al\u0131n\u0131r.\u2028\u2028\u0130kili test i\u00e7in ultrasonda fetusun Ense Kal\u0131nl\u0131\u011f\u0131 (NT, ense pilisi kal\u0131nl\u0131\u011f\u0131, nuchal translucency) d\u0131\u015f\u0131nda, ayn\u0131 zamanda CRL (crown rump lenght, ba\u015f-popo aras\u0131 mesafe) \u00f6l\u00e7\u00fcmleri de yap\u0131l\u0131r.<\/p>\n

4 ) \u0130kili test pozitif \u00e7\u0131karsa ne yap\u0131lmal\u0131?\u2028<\/strong><\/p>\n

Testin pozitif (tarama-pozitif) olmas\u0131 halinde, yap\u0131lmas\u0131 gereken ileri a\u015fama, \u201ckoryon vill\u00fcs biyopsisi\u201d olarak ifade edilen, plasentan\u0131n bebe\u011fe ait b\u00f6lgesinden k\u00fc\u00e7\u00fck bir par\u00e7a al\u0131narak, kromozom bak\u0131m\u0131ndan analizi ile kesin te\u015fhisin yap\u0131lmas\u0131n\u0131n sa\u011flanmas\u0131d\u0131r. Ayn\u0131 zamanda fetusa ayr\u0131nt\u0131l\u0131 bir \u015fekilde ultrason incelemesinin yap\u0131lmas\u0131 da tavsiye edilmektedir.\u2028\u0130kinci bir method ise gebeli\u011fin 16. haftas\u0131nda amniyosentez i\u015fleminin yap\u0131lmas\u0131d\u0131r.\u2028\u2028Amniyosentez ve koryon villus biyopsisi s\u0131ras\u0131nda, bebe\u011fin kromozonlar\u0131 incelenerek net bir sonucun elde edilebilmesi m\u00fcmk\u00fcnd\u00fcr. Bu sebepten dolay\u0131, her iki test \u201cdiyagnostik test (tan\u0131sal test)\u201d olarak ge\u00e7er.<\/p>\n

5 ) \u0130kili testin negatif \u00e7\u0131kmas\u0131 halinde yap\u0131lmas\u0131 gereken \u015fey nedir?<\/strong><\/p>\n

Testin negatif \u00e7\u0131kmas\u0131, down sendromu ihtimalinden uzakla\u015ft\u0131rmak ile beraber, bebe\u011finizin tam anlam\u0131 ile sa\u011fl\u0131kl\u0131 oldu\u011funu da g\u00f6stermez. Bu debepten dolay\u0131 da, d\u00fczenli bir \u015fekilde hamilelik izlenimlerinize devam etmenizi tavsiye ediyoruz.
\nAyn\u0131 zamanda ikili test (double test), bebe\u011fin NTD (n\u00f6ral t\u00fcp defektleri) ile alakal\u0131 olan k\u0131sm\u0131 ile ilgili de doktorlara bilgi vermektedir. Bu konuda \u00fc\u00e7l\u00fc tarama testinde yer alan AFP seviyeleri \u00e7ok \u00f6nemlidir. \u00dc\u00e7l\u00fc test, hamilelik d\u00f6neminin 16. \u0130le 18. Hamilelik haftalar\u0131 aras\u0131nda yap\u0131lmaktad\u0131r.<\/p>\n

6 ) 11 ile 14 hafta testi (ikili test) nelerden olu\u015fur? Down sendromu saptama y\u00fczdesi ka\u00e7t\u0131r?<\/strong><\/p>\n

Hamilelik d\u00f6neminin 11 ile 14. Haftalar\u0131 aras\u0131nda ger\u00e7ekle\u015ftirilen risk hesaplanma analizinde, annenin ya\u015f\u0131, anne kan\u0131nda \u00f6l\u00e7\u00fclen PAPP-A ve Free Beta hCG seviyeleri ultrason yard\u0131m\u0131 ile \u00f6l\u00e7\u00fclen fet\u00fcs\u00fcn ense kal\u0131nl\u0131\u011f\u0131, bebe\u011fin burun kemi\u011fi, bebe\u011fin kalp ve duktus venozusunda yer alan kan ak\u0131mlar\u0131n\u0131n kat\u0131l\u0131m\u0131 ile verilir. Down sendromu saptama oran\u0131, b\u00fct\u00fcn bulgular ile beraber, yakla\u015f\u0131k %97.5 civar\u0131ndad\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u0130kili…<\/p>\n","protected":false},"author":4,"featured_media":6953,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1523],"tags":[4172,4175,4176,4177,4179,4174,4178,4173],"_links":{"self":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/6951"}],"collection":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/comments?post=6951"}],"version-history":[{"count":0,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/6951\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media\/6953"}],"wp:attachment":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media?parent=6951"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/categories?post=6951"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/tags?post=6951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}