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{"id":6880,"date":"2015-12-22T09:33:43","date_gmt":"2015-12-22T07:33:43","guid":{"rendered":"https:\/\/www.coolkadin.com\/?p=6880"},"modified":"2015-12-22T09:34:08","modified_gmt":"2015-12-22T07:34:08","slug":"embriyo-dondurma","status":"publish","type":"post","link":"https:\/\/www.coolkadin.com\/embriyo-dondurma.html","title":{"rendered":"EMBR\u0130YO DONDURMA"},"content":{"rendered":"

Embriyo dondurma y\u00f6ntemi y\u0131llarca uygulanan ve yeni yeni fark edilen y\u00f6ntemlerden biridir. T\u00fcp bebek laboratuvarlar\u0131nda 20 \u2013 25 y\u0131ld\u0131r uygulanmakta olan embriyo dondurma ve \u00e7\u00f6zme y\u00f6ntemi ile son y\u0131llarda geli\u015ftirilen yeni teknikler sayesinde \u00e7ok daha y\u00fcksek oranlarda gebelikler elde etmek m\u00fcmk\u00fcn olmaktad\u0131r.<\/p>\n

\u00dcnitemizde eskiden uygulanan slow (yava\u015f) dondurma y\u00f6ntemi yerine \u00e7ok daha ba\u015far\u0131l\u0131 vitrifikasyon (h\u0131zl\u0131) dondurma y\u00f6ntemi uygulanmaktad\u0131r.<\/p>\n

Embriyolar kriyoprotektan ad\u0131 verilen kimyasal maddeler sayesinde dondurulup -196 \u00b0C\u2019de s\u0131v\u0131 nitrojen tanklar\u0131 i\u00e7inde ki\u015fiye \u00f6zel b\u00f6lgelerinde saklan\u0131rlar. \u0130stendi\u011finde bu embriyolar tersine uygulanan i\u015flemlerle \u00e7\u00f6z\u00fcl\u00fcp ana rahmine transfer edilir. S\u0131v\u0131 nitrojen i\u00e7erisinde t\u00fcm kimyasal reaksiyonlar ve h\u00fccresel aktiviteler durmaktad\u0131r. Bu durum bir t\u00fcr h\u00fccresel uyku halidir. Yap\u0131lan deneysel \u00e7al\u0131\u015fmalarda embriyolar\u0131n s\u0131v\u0131 nitrojen i\u00e7erisinde uzun s\u00fcre sa\u011fl\u0131kl\u0131 bir \u015fekilde saklanabilece\u011fi g\u00f6sterilmi\u015ftir.<\/p>\n

\u00dcnitemizde genellikle 3.g\u00fcn ve 5.g\u00fcn embriyo dondurma (vitrifkasyon) i\u015flemi yap\u0131lmaktad\u0131r. Dondurulan embriyolar\u0131n iyi kalitede olmas\u0131 \u00e7\u00f6zme i\u015fleminde embriyolar\u0131n canl\u0131 olarak geri d\u00f6nme oran\u0131na do\u011frudan etki etmektedir.<\/p>\n

Hangi Durumlarda Embriyo Dondurma Yap\u0131l\u0131r?
\n1- Transfer i\u015fleminden sonra geriye kalan kaliteli embriyolar imha edilmek yerine dondurulup tekrar transfer edilmek i\u00e7in saklanabilir.<\/p>\n

2- \u0130la\u00e7larla yumurtal\u0131klar\u0131n uyar\u0131lmas\u0131 esnas\u0131nda OHSS (a\u015f\u0131r\u0131 uyar\u0131lma sendromu) riski olan kad\u0131nlarda t\u00fcm embriyolar daha sonra kullan\u0131lmak \u00fczere dondurulabilir.<\/p>\n

3- Rahim i\u00e7ini saran endometrium dokusunun yeteri kadar geli\u015femedi\u011fi durumlarda.<\/p>\n

4- Rahim i\u00e7i cerrahi operasyon gereken durumlarda.<\/p>\n

5- Kemoterapi veya radyoterapi gerektiren kanser tedavilerinden \u00f6nce embriyolar dondurulabilir.<\/p>\n

Embriyo Dondurman\u0131n \u00c7iftlere Kazand\u0131rd\u0131klar\u0131<\/p>\n

Bir t\u00fcp bebek \u00fcnitesinde embriyo dondurma i\u015fleminin yap\u0131labilmesi \u00e7iftlere sa\u011flad\u0131\u011f\u0131 avantajlar a\u00e7\u0131s\u0131ndan \u00f6nemli bir husustur. Taze bir siklusta daha az ( 1 \u2013 2 ) embriyo transfer edilip geri kalan embriyolar\u0131n dondurulmas\u0131 , riskli bir gebelik s\u00fcreci olan \u00e7o\u011ful gebelik ihtimalini azalt\u0131r. \u00c7iftlere as\u0131l ama\u00e7 olan sa\u011fl\u0131kl\u0131 bir gebelik ve do\u011fum imkan\u0131 sa\u011flar.<\/p>\n

Dondurulan embriyolar\u0131n \u00e7\u00f6z\u00fclerek transfer edilmesi \u00e7iftlere \u00e7ok daha az harcama yaparak neredeyse taze bir denemeye yak\u0131n gebelik \u015fans\u0131 sunar. \u00dcstelik uzun s\u00fcreli ila\u00e7 kullan\u0131m\u0131, yumurta toplanmas\u0131 ve ICSI (yumurtaya sperm enjeksiyonu) gibi i\u015flemlere gerek kalmaz. Ayr\u0131ca gebelik elde edilmi\u015f \u00e7iftlerde ikinci bir \u00e7ocuk istemi dondurulan embriyolar\u0131n \u00e7\u00f6z\u00fcl\u00fcp transfer edilmesi ile m\u00fcmk\u00fcn olabilir.<\/p>\n

Dondurulan Embriyolar\u0131n Saklama S\u00fcresi
\nYap\u0131lan bilimsel \u00e7al\u0131\u015fmalar dondurulmu\u015f embriyolar\u0131n 10-15 sene gibi \u00e7ok uzun s\u00fcre sonra \u00e7\u00f6z\u00fcld\u00fc\u011f\u00fcnde bile sa\u011fl\u0131kl\u0131 gebelik \u015fans\u0131 verdi\u011fini g\u00f6stermi\u015ftir. Ancak \u00fclkemizde Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131n\u0131n ilgili y\u00f6netmeli\u011fi gere\u011fince dondurulmu\u015f embriyolar 5 y\u0131l boyunca s\u0131v\u0131 nitrojen i\u00e7erisinde saklanabilmektedir.<\/p>\n

Vitrifikasyon Y\u00f6ntemi ile Embriyo Dondurma<\/p>\n

Vitrifikasyon dondurma y\u00f6ntemi di\u011fer dondurma y\u00f6ntemi (konvansiyonel yava\u015f dondurma) ile k\u0131yasland\u0131\u011f\u0131nda \u00e7ok daha \u00fcst\u00fcn bir teknik oldu\u011funu kan\u0131tlam\u0131\u015ft\u0131r. Bu y\u00f6ntem ile dondurulan embriyolar \u00e7\u00f6z\u00fcld\u00fc\u011f\u00fcnde %90 \u2013 100 oran\u0131nda canl\u0131 ve sa\u011fl\u0131kl\u0131 bir \u015fekilde geri d\u00f6nmektedir. Burada dikkat edilmesi gereken nokta dondurulan embriyolar\u0131n kalitelerinin dondurulmaya uygun olmas\u0131d\u0131r.<\/p>\n

Br\u00fcksel T\u00fcp Bebek \u00dcnitesi t\u00fcm di\u011fer t\u00fcp bebek tekniklerde oldu\u011fu gibi vitrifikasyon y\u00f6ntemindeki t\u00fcm geli\u015fmeleri an\u0131nda takip etmekte ve daha y\u00fcksek ba\u015far\u0131lar elde etmek i\u00e7in bilimsel \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcrmektedir. Yapt\u0131\u011f\u0131m\u0131z \u00e7al\u0131\u015fmalar sayesindedir ki, \u00fcnitemizde vitrifikasyon y\u00f6ntemi ile neredeyse taze embriyo transferlerinki kadar y\u00fcksek gebelik oranlar\u0131 elde edilebilmektedir.<\/p>\n

Sundu\u011fu avantajlar g\u00f6z \u00f6n\u00fcne al\u0131nd\u0131\u011f\u0131nda embriyo dondurmaya uygun oldu\u011funu g\u00f6rd\u00fc\u011f\u00fcm\u00fcz t\u00fcm \u00e7iftlere, transfer g\u00fcn\u00fc ekibimiz taraf\u0131ndan bilgilendirme ve embriyolar\u0131n dondurulmas\u0131 \u00f6nerisi yap\u0131lmaktad\u0131r.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Embriyo…<\/p>\n","protected":false},"author":1,"featured_media":6881,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1523],"tags":[587,169,1373,225,4031,471,404,153],"_links":{"self":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/6880"}],"collection":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/comments?post=6880"}],"version-history":[{"count":0,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/6880\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media\/6881"}],"wp:attachment":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media?parent=6880"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/categories?post=6880"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/tags?post=6880"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}