1 ) \u0130leri ya\u015fta baba olmak, beraberinde hangi riskleri getirir?<\/strong><\/p>\n

Hamilelik ve k\u0131s\u0131rl\u0131k (infertilite) konusu, as\u0131l itibari ile anne ya\u015f\u0131 ile olduk\u00e7a yak\u0131ndan ilgilidir. Annenin ya\u015f\u0131 artt\u0131k\u00e7a, \u00f6zellikle de 35 ya\u015f\u0131ndan sonra hem hamile olamama, yani k\u0131s\u0131rl\u0131k ile alakal\u0131 bir tak\u0131m risk art\u0131\u015f\u0131na rastlan\u0131r, hem de hamile olduktan bir m\u00fcddet sonra hamilelik s\u00fcresinde anne ve bebek ile alakal\u0131 bir tak\u0131m risklerde art\u0131\u015f g\u00f6r\u00fcl\u00fcr.<\/p>\n

2 ) Baba aday\u0131n\u0131n ya\u015f\u0131 b\u00fcy\u00fcd\u00fck\u00e7e k\u0131s\u0131rl\u0131k riskinde de art\u0131\u015f olur mu?<\/strong><\/p>\n

Baba aday\u0131n\u0131n ya\u015f\u0131, her ne kadar annenin ya\u015f\u0131 kadar \u00f6nemli olmasa da, baz\u0131 konularda ilerleyen ya\u015flarda \u00e7e\u015fitli riskleri beraberinde getirir. Baba aday\u0131n\u0131n ya\u015f\u0131 artt\u0131k\u00e7a, genellikle de 40 ile 45 ya\u015flar\u0131n\u0131n ard\u0131ndan sperm hareketi, hacmi ve normal \u015fekilli sperm say\u0131s\u0131 (morfoloji) azal\u0131r. Ancak sperm konsantrasyonunda ya\u015f artt\u0131k\u00e7a herhangi bir de\u011fi\u015fiklik olmaz. Sperm parametrelerinde meydana gelen bozulmalar sebebi ile erke\u011fin ya\u015f\u0131n\u0131n ileri olmas\u0131, kad\u0131n\u0131n ya\u015f\u0131 kadar etkilemese de, hamileli\u011fin meydana gelmesi konusunda ba\u015far\u0131y\u0131 azalt\u0131r. Hamileli\u011fin meydana gelmesi daha uzun s\u00fcre al\u0131r ve hamilelik oran\u0131 d\u00fc\u015fer.<\/p>\n

3 ) Hamilelik ile alakal\u0131 meydana gelebilecek riskler ve bebekte ortaya \u00e7\u0131kabilecek hastal\u0131klar nelerdir?<\/strong><\/p>\n

\u00dclkemizde ki kad\u0131nlarda, ortalama 46 ile 50 ya\u015f aras\u0131nda menopoz d\u00f6neminin ba\u015flamas\u0131 ile beraber, yumurta h\u00fccresinin \u00fcretimi durur. Erkeklerde her ya\u015fta sperm \u00fcretimi devam eder, ancak ileri ya\u015flarda sperm kalitesinde azalmalar g\u00f6r\u00fcl\u00fcr. Ya\u015f\u0131 b\u00fcy\u00fck olan erkeklerde, sperm \u00fcretimi esnas\u0131nda genetik hata yani mutasyon olu\u015fma tehlikesinde art\u0131\u015f olur. Bu mutasyonlar hem d\u00fc\u015f\u00fck olu\u015fma riskinde hafif bir art\u0131\u015fa sebebiyet verir, hem de bebekte bir tak\u0131m hastal\u0131klar\u0131n geli\u015fimine yatk\u0131nl\u0131k olu\u015fturur. Daha \u00e7ok, otozomal dominant hastal\u0131klar\u0131n bebekte meydana gelme riski artar. \u00c7\u00fcnk\u00fc bu hastal\u0131klar gen \u00e7iftlerinden yaln\u0131zca bir tanesinde hata olmas\u0131 sebebi ile beraber ortaya \u00e7\u0131kabilir. Erke\u011fin sperminde meydana gelebilecek genetik hata, bu hastal\u0131klar\u0131n meydana \u00e7\u0131kmas\u0131na sebep olabilir. Otozomal dominant hastal\u0131klardan baz\u0131lar\u0131: Akondroplazi, n\u00f6rofibromatozis, Marfan sendromu, osteogenezis imperfekta<\/p>\n

Baba aday\u0131n\u0131n ya\u015f\u0131n\u0131n b\u00fcy\u00fck olmas\u0131 ile beraber, bebekte otizm, \u015fizofreni, bipolar bozukluk, konsantrasyon bozuklu\u011fu, alg\u0131lama yetene\u011finde d\u00fc\u015f\u00fckl\u00fck, kognitif fonksiyonlarda bozukluk gibi baz\u0131 hastal\u0131klarda art\u0131\u015f g\u00f6r\u00fcld\u00fc\u011f\u00fcn\u00fc bildiren ara\u015ft\u0131rmalar vard\u0131r.<\/p>\n

Babada k\u0131s\u0131rl\u0131k<\/strong><\/p>\n

4 ) D\u00fc\u015f\u00fck riski:<\/strong><\/p>\n

Yap\u0131lan ara\u015ft\u0131rmalar b\u00fcy\u00fck bir k\u0131sm\u0131nda, baba aday\u0131n\u0131n ya\u015f\u0131n\u0131n ileri olmas\u0131n\u0131n, kad\u0131n\u0131n ya\u015f\u0131ndan ba\u011f\u0131ms\u0131z olarak d\u00fc\u015f\u00fck bak\u0131m\u0131ndan ciddi oranda risk art\u0131\u015f\u0131na sebep oldu\u011funu g\u00f6stermi\u015ftir. Anne aday\u0131n\u0131n ya\u015f\u0131 ilerledik\u00e7e de, elde edilen bu hamileli\u011fin d\u00fc\u015f\u00fck ile sonu\u00e7lanma riski artar.<\/p>\n

Baba ve k\u0131s\u0131rl\u0131k<\/strong><\/p>\n

5 ) Down sendromu ile ileri baba ya\u015f\u0131 aras\u0131ndaki ili\u015fki nedir?<\/strong><\/p>\n

Bebekte down sendromu olma riski, anne aday\u0131n\u0131n ya\u015f\u0131 b\u00fcy\u00fcd\u00fck\u00e7e artar, arada ciddi bir orant\u0131 vard\u0131r. Baba aday\u0131n\u0131n ya\u015f\u0131n\u0131n down sendromu riskine etki etmedi\u011fini g\u00f6steren baz\u0131 ara\u015ft\u0131rmalar\u0131n beraberinde, yap\u0131lan bir tak\u0131m \u00f6nemli ara\u015ft\u0131rmalar da, anne aday\u0131n\u0131n ya\u015f\u0131 35 den b\u00fcy\u00fck olmas\u0131 halinde, baba aday\u0131n\u0131n ya\u015f\u0131n\u0131n da ileri olmas\u0131n\u0131n riski daha fazla artt\u0131rd\u0131\u011f\u0131 \u015feklinde ifade sunmu\u015ftur.<\/p>\n

 <\/p>\n

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