Ha\u015fimato hastal\u0131\u011f\u0131\u00a0di\u011fer ad\u0131yla\u00a0Ha\u015fimato tiroidi (tiroiditi), ilk kez 1912 y\u0131l\u0131nda japon cerrah\u00a0Hakaru Hashimoto taraf\u0131ndan tan\u0131mlanm\u0131\u015f olup, kendi ad\u0131yla an\u0131lmaktad\u0131r.<\/p>\n

Ha\u015fimato tiroidi,<\/strong>\u00a0savunma sisteminin tiroid bezindeki baz\u0131 yap\u0131lara sald\u0131rd\u0131\u011f\u0131 ve burada iltihaba neden oldu\u011fu\u00a0otoimm\u00fcn bir hastal\u0131kt\u0131r. Savunma sistemi normalde v\u00fccuda giren yabanc\u0131 maddelere (vir\u00fcs gibi) sald\u0131rarak, v\u00fccudu korur. E\u011fer bu sistem kendi sa\u011fl\u0131kl\u0131 h\u00fccrelerini yabanc\u0131 gibi alg\u0131lay\u0131p bunlara sald\u0131r\u0131rsa, bir dizi hastal\u0131k ortaya \u00e7\u0131kar. Bu hastal\u0131klara otoimm\u00fcn hastal\u0131klar denmektedir. Bu hastal\u0131klar ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin hatal\u0131 yan\u0131t\u0131 sonucu olu\u015furlar.<\/p>\n

Ha\u015fimato hastal\u0131\u011f\u0131nda ise ba\u011f\u0131\u015f\u0131kl\u0131k sistemi, tiroid bezine sald\u0131rmaktad\u0131r. Bu sald\u0131r\u0131daki temel savunma h\u00fccreleri lenfositlerdir. Bundan dolay\u0131 bu hastal\u0131\u011fa\u00a0kronik lenfositik tiroidit\u00a0de denir.<\/p>\n

Otoimm\u00fcn hastal\u0131klar genel olarak kad\u0131nlarda daha s\u0131k g\u00f6r\u00fcl\u00fcrler. Ha\u015fimato hastal\u0131\u011f\u0131, kad\u0131nlarda yakla\u015f\u0131k 7 kat daha s\u0131k g\u00f6r\u00fclmektedir.Savunma sisteminin sald\u0131r\u0131s\u0131, tiroid bezinin yeterli hormon \u00fcretmesini genellikle engeller. Sonu\u00e7ta tiroid hormon seviyeleri d\u00fc\u015fer yani hipotiroidi geli\u015fir. Ayr\u0131ca baz\u0131 ki\u015filerde bu iltihabi durum, tiroid bezinin b\u00fcy\u00fcmesine yani guatra neden olur.<\/p>\n

Neden Olur?<\/h2>\n

Ha\u015fimato hastal\u0131\u011f\u0131n\u0131n neden geli\u015fti\u011fi tam olarak bilinmemektedir. Yani savunma sisteminin tiroid bezine sald\u0131rmas\u0131n\u0131n nedeni tam olarak a\u00e7\u0131klanmam\u0131\u015ft\u0131r. Ancak bu konuda \u00e7e\u015fitli risk fakt\u00f6rleri bulunmaktad\u0131r. Bu fakt\u00f6rler hastal\u0131\u011f\u0131n geli\u015fme olas\u0131l\u0131\u011f\u0131n\u0131 artt\u0131rmaktad\u0131r. Ha\u015fimato tiroidi risk fakt\u00f6rleri;<\/p>\n

\n
• Genetik Ge\u00e7i\u015f<\/strong>: Ailesinde Ha\u015fimato tiroidi (tiroiditi) veya di\u011fer otoimm\u00fcn hastal\u0131klar (\u00e7\u00f6l yak hastal\u0131\u011f\u0131 gibi) bulunan ki\u015filerde daha s\u0131k g\u00f6r\u00fcl\u00fcr. Tek yumurta ikizlerinde hastal\u0131k %40 oran\u0131nda iki bireyde de g\u00f6r\u00fcl\u00fcr.<\/li>\n
• Hormonlar<\/strong>: Gerek kad\u0131nlarda daha s\u0131k g\u00f6r\u00fclmesi gerekse do\u011fum sonras\u0131ndaki ilk senede daha s\u0131k rastlanmas\u0131 nedeniyle cinsiyet hormonlar\u0131n\u0131n etkisinin oldu\u011fu d\u00fc\u015f\u00fcn\u00fclmektedir.<\/li>\n
• Radyasyon Maruziyeti:<\/strong>\u00a0\u00c7e\u015fitli nedenlerle ba\u015f-boyun b\u00f6lgesinin radyasyona maruz kalmas\u0131 Ha\u015fimato tiroiditi riskini artt\u0131r\u0131r.<\/li>\n
• A\u015f\u0131r\u0131 \u0130yot Al\u0131m\u0131:<\/strong>\u00a0Diyette a\u015f\u0131r\u0131 iyot al\u0131m\u0131 hastal\u0131\u011f\u0131n geli\u015fme riskini artt\u0131r\u0131r.<\/li>\n
• \u0130la\u00e7lar:<\/strong>\u00a0Baz\u0131 ila\u00e7lar Ha\u015fimato hastal\u0131\u011f\u0131 riskini artt\u0131rmaktad\u0131r. Lityum, amiodaron, talidomid, tirozin kinaz inhibit\u00f6rleri, diftidox, alemtuzumab, interferon alfa gibi\u2026<\/li>\n
• Hepatit C olan ki\u015filerde bu hastal\u0131\u011fa daha s\u0131k rastlan\u0131r.<\/li>\n
• Selenyum eksikli\u011fi ve baz\u0131 bula\u015f\u0131c\u0131 ajanlar Ha\u015fimato tiroidi riskini artt\u0131rmaktad\u0131r.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

  Ha\u015fimato…<\/p>\n","protected":false},"author":15,"featured_media":6731,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1579,138],"tags":[],"_links":{"self":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/110295"}],"collection":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/comments?post=110295"}],"version-history":[{"count":1,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/110295\/revisions"}],"predecessor-version":[{"id":110296,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/110295\/revisions\/110296"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media\/6731"}],"wp:attachment":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media?parent=110295"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/categories?post=110295"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/tags?post=110295"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}