Epigenetik de\u011fi\u015fiklikler, genlerimizi a\u00e7\u0131p kapatan kimyasal de\u011fi\u015fikliklerdir.Yeni bir ara\u015ft\u0131rmada, ara\u015ft\u0131rmac\u0131lar, kad\u0131nlarda \u00e7ay t\u00fcketiminin, epigenetik de\u011fi\u015fikliklere neden oldu\u011funu ke\u015ffettiler. Ara\u015ft\u0131rmaya g\u00f6re \u00e7ay\u0131n kad\u0131nlarda kanser ve \u00f6strojen metabolizmas\u0131 ile etkile\u015fime girdi\u011fi bilinen genlerde epigenetik de\u011fi\u015fikliklere neden oldu\u011fu belirtildi.<\/p>\n

Sonu\u00e7lar Human Molecular Genetics dergisinde\u00a0yay\u0131nland\u0131. Epigenetik de\u011fi\u015fiklikler, genlerimizi a\u00e7\u0131p kapatan kimyasal de\u011fi\u015fikliklerdir.\u00a0Yiyecek se\u00e7imi, sigara i\u00e7me ve kimyasallara maruz kalma gibi \u00e7evre ve ya\u015fam tarz\u0131 fakt\u00f6rlerinin epigenetik de\u011fi\u015fikliklere neden olabilece\u011fi iyi bilinmektedir.<\/p>\n

Uppsala \u00dcniversitesi\u2019nden ara\u015ft\u0131rmac\u0131lar Avrupa\u2019daki ara\u015ft\u0131rma gruplar\u0131yla i\u015fbirli\u011fi i\u00e7inde, kahve ve \u00e7ay t\u00fcketiminin epigenetik de\u011fi\u015fikliklere neden olup olmayaca\u011f\u0131n\u0131 ara\u015ft\u0131rd\u0131.<\/p>\n

\u00d6nceki \u00e7al\u0131\u015fmalar, hem kahve hem de \u00e7ay\u0131n, insanlardaki hastal\u0131k riskini, t\u00fcm\u00f6r progresyonunu bask\u0131lad\u0131\u011f\u0131n\u0131, inflamasyonu azaltt\u0131\u011f\u0131n\u0131 ve \u00f6strojen metabolizmas\u0131n\u0131 etkiledi\u011fini g\u00f6steriyordu. Bu ara\u015ft\u0131rmada bahsedilen fakt\u00f6rlerin epigenetik de\u011fi\u015fikliklerden kaynakl\u0131 mekanizmalar olu\u015fturarak genlerde \u00f6nemli bir rol oynad\u0131\u011f\u0131 ileri s\u00fcr\u00fcld\u00fc.<\/p>\n

Sonu\u00e7lar, \u00e7ay t\u00fcketiminin kad\u0131nlarda epigenetik de\u011fi\u015fikliklere neden olurken, erkekleri ise etkilemedi\u011fini g\u00f6stermektedir.<\/p>\n

 <\/p>\n

<\/p>\n

\u0130lgin\u00e7tir ki, bu epigenetik de\u011fi\u015fikliklerin bir\u00e7o\u011fu kanser ve \u00f6strojen metabolizmas\u0131nda yer alan genlerde bulunmu\u015ftur.\u00a0\u00d6nceki ara\u015ft\u0131rmalar, \u00e7ay t\u00fcketiminin \u00f6strojen d\u00fczeylerini d\u00fc\u015f\u00fcrd\u00fc\u011f\u00fcn\u00fc ve erkeklerde ve kad\u0131nlarda \u00e7ay\u0131n biyolojik tepkisi aras\u0131nda potansiyel bir fark oldu\u011funu g\u00f6steriyor.<\/p>\n

Kad\u0131nlar ayr\u0131ca erkeklerle kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda daha y\u00fcksek miktarda \u00e7ay i\u00e7iyorlar ve bu da kad\u0131nlarda birliktelik bulmak i\u00e7in g\u00fcc\u00fcm\u00fcz\u00fc art\u0131r\u0131yor \u201cdiyor, ara\u015ft\u0131rmaya \u00f6nc\u00fcl\u00fck eden \u0130mm\u00fcnoloji, Genetik ve Patoloji Departman\u0131 ara\u015ft\u0131rmac\u0131s\u0131 Weronica Ek.<\/p>\n

\u00c7al\u0131\u015fma\u00a0kahve i\u00e7en bireylerde<\/strong>\u00a0herhangi bir epigenetik de\u011fi\u015fiklik bulamad\u0131.<\/p>\n

Bu \u00e7al\u0131\u015fmadan elde edilen sonu\u00e7lar, \u00e7ay potansiyelinin epigenetik de\u011fi\u015fikliklerden kaynaklanabilece\u011fini yans\u0131tabilen, kanser ve \u00f6strojen metabolizmas\u0131na kar\u0131\u015fan \u00e7aydaki farmakolojik aktif bile\u015fenlerin rol\u00fcn\u00fc vurgulamakta.<\/p>\n

Bununla birlikte, bu \u00e7al\u0131\u015fman\u0131n sa\u011fl\u0131kl\u0131 olup olmad\u0131\u011f\u0131, \u00e7al\u0131\u015fmada izlenen ki\u015filerin genetik olarak sa\u011fl\u0131kl\u0131 olup olmad\u0131\u011f\u0131na ba\u011fl\u0131d\u0131r. Ve bu \u00e7al\u0131\u015fmada bulunan epigenetik de\u011fi\u015fikliklerin sa\u011fl\u0131\u011f\u0131m\u0131z\u0131 nas\u0131l etkiledi\u011fini anlamak i\u00e7in daha fazla ara\u015ft\u0131rmaya ihtiya\u00e7 vard\u0131r.<\/p>\n

Daha \u00f6nce yap\u0131lan ara\u015ft\u0131rmalarda \u00e7aydaki \u201ccatechins\u201dmaddesinin k\u00fclt\u00fcrl\u00fc kanser h\u00fccrelerinde epigenetik de\u011fi\u015fikli\u011fe yol a\u00e7t\u0131\u011f\u0131 ve \u00e7ay\u0131n baz\u0131 sa\u011fl\u0131k etkilerinin epigenetik arac\u0131l\u0131\u011fa neden olabilece\u011fini savunulmu\u015ftu.<\/p>\n","protected":false},"excerpt":{"rendered":"

Epigenetik…<\/p>\n","protected":false},"author":15,"featured_media":74905,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1579,138],"tags":[],"_links":{"self":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/110102"}],"collection":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/comments?post=110102"}],"version-history":[{"count":1,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/110102\/revisions"}],"predecessor-version":[{"id":110103,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/posts\/110102\/revisions\/110103"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media\/74905"}],"wp:attachment":[{"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/media?parent=110102"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/categories?post=110102"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.coolkadin.com\/wp-json\/wp\/v2\/tags?post=110102"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}